Search for Hypercholesterolemia

Pure hypercholesterolemia: Causes, symptoms, and treatment.
Two forms of the condition exist: heterozygous familial hypercholesterolemia HeFH and homozygous familial hypercholesterolemia HoFH. The HeFH condition occurs when a person inherits pure hypercholesterolemia from one parent. The HoFH condition occurs when a person inherits pure hypercholesterolemia from both parents.
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Hypercholesterolemia Symptoms, diagnosis and treatment BMJ Best Practice.
Hypercholesterolemia, an elevation of total cholesterol TC and/or low-density lipoprotein LDL-cholesterol or non-HDL-cholesterol defined as the subtraction of high-density lipoprotein HDL-cholesterol from total cholesterol in the blood, is also often referred to as dyslipidemia, to encompass the fact that it might be accompanied by a decrease in HDL-cholesterol or an increase in triglycerides.
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Types of Hypercholesterolemia Medications You Should Know.
Familial hypercholesterolemia runs in families, regardless of how healthy a persons diet or exercise habits may be. Fortunately, there are hypercholesterolemia medications for individuals whose cholesterol levels remain high even with healthy lifestyle habits. Here are a few you should know about.
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Hypercholesterolemia Wikipedia.
Genetic abnormalities are in some cases completely responsible for hypercholesterolemia, such as in familial hypercholesterolemia, where one or more genetic mutations in the autosomal dominant APOB gene exist, the autosomal recessive LDLRAP1 gene, autosomal dominant familial hypercholesterolemia HCHOLA3 variant of the PCSK9 gene, or the LDL receptor gene.
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What is Hypercholesterolemia?
However, whether or not a lipid profile is considered safe or not also depends on whether a person is at risk of or has heart disease. Patients diagnosed with hypercholesterolemia are advised to modify their diet and engage in regular physical activity.
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The side effects were mild, and no clinically significant elevations in alanine aminotransferase, creatine kinase, or creatinine were seen. The authors concluded that the efficacy in children with slight or moderate hypercholesterolemia was satisfactory, but in children with severe hypercholesterolemia it was insufficient.
Familial hypercholesterolemia Symptoms and causes Mayo Clinic.
Familial hypercholesterolemia affects the way the body processes cholesterol. As a result, people with familial hypercholesterolemia have a higher risk of heart disease and a greater risk of early heart attack. The gene that causes familial hypercholesterolemia is inherited. The condition is present from birth.
Hypercholesterolemia Genetics Home Reference NIH.
Less commonly, hypercholesterolemia can be caused by mutations in the APOB, LDLRAP1, or PCSK9 gene. Changes in the APOB gene result in a form of inherited hypercholesterolemia known as familial defective apolipoprotein B-100 FDB. LDLRAP1 mutations are responsible for another type of inherited high cholesterol, autosomal recessive hypercholesterolemia ARH.
Hypercholesterolemia an overview ScienceDirect Topics. ScienceDirect. Elsevier. RELX Group.
Hypercholesterolemia is usually recognized as a secondary hyperlipidemia in animals, associated with an underlying disorder such as hypothyroidism, hypersomatotropism growth hormone GH excess, Cushings-like disease or syndrome, or diabetes mellitus although some families of Doberman pinschers and rottweilers have been reported to exhibit a primary hypercholesterolemia.

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