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Article The Role of Hyperimmune Globulins.
Passive immunization with hyperimmune globulin may be appropriate in the following circumstances: when the patient cannot synthesize antibody; when the patient has been exposed to a disease to which they cannot mount an adequate immune response or that is likely to cause complications; or when the patient has contracted a disease and the effects of an associated toxin must be ameliorated.
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Hyperimmune globulin Wikipedia.
Hyperimmune globulin is similar to intravenous immunoglobulin IVIG except that it is prepared from the plasma of donors with high titers of antibody against a specific organism or antigen Some agents against which hyperimmune globulins are available include hepatitis B, rabies, tetanus toxin, varicella-zoster, etc.
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Hyperimmune Globulin an overview ScienceDirect Topics. ScienceDirect. Elsevier. RELX Group.
A later study identified a higher survival rate to discharge for septic and critically ill foals receiving hyperimmune plasma rich in antiendotoxin antibodies; however, survival rate in a subset of the foal population that had gram-negative septicemia was not significantly altered by plasma administration.
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Hyperimmune definition of hyperimmune by Medical dictionary.
have developed a novel, antibiotic-free method that uses hyperimmune egg yolk antibodies to control intestinal poultry diseases. Cracking down on poultry disease with egg yolk. Effect of hyperimmune plasma on the severity of pneumonia caused by Rhodococcus equi in experimental infected foals.
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Production and characterization of a human hyperimmune intravenous immunoglobulin against Pseudomonas aeruginosa and Klebsiella species. PubMed NCBI.
Production and characterization of a human hyperimmune intravenous immunoglobulin against Pseudomonas aeruginosa and Klebsiella species. Cryz SJ Jr 1, F├╝rer E, Sadoff JC, Fredeking T, Que JU, Cross AS. Swiss Serum and Vaccine Institute, Bern. A hyperimmune globulin for intravenous use H-IVIG was prepared from the plasma of donors immunized with Pseudomonas aeruginosa and Klebsiella vaccines.
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Hyperimmune and Autoimmune Diseases SpringerLink.
Immunologic responses to exogenous or autologous substances sometimes initiate chemical mediator and effector cell responses that go beyond protection of the host from the antigen to injury of the host. Diseases which can be attributed to immunopathologic injury are termed allergic, immunological, hyperimmune, or autoimmune when autologous antigens initiate the immune response.
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Hyperimmune Definition of Hyperimmune by Merriam-Webster.
a of a serum: containing exceptionally large quantities of an antibody hyperimmune serum produced by serial innoculations. b of an antibody: derived from the hyperimmune sera of multiple donors hyperimmune IgG preparations administered to patients following exposure to hepatitis B.
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Hyperimmune Globulin an overview ScienceDirect Topics. ScienceDirect. Elsevier. RELX Group.
In former times, postexposure prophylaxis PEP by using TBE hyperimmune globulin within 96 hours for passive immunization after a tick bite was practiced. However, TBE hyperimmune globulin is no longer available, and standard lots of commercially available human immune globulin are untested as PEP and unlikely to contain a sufficient level of specific antibodies to protect against this infection.
In vitro evaluation of cytomegalovirus-specific hyperimmune globulins vs. standard intravenous immunoglobulins. PubMed NCBI.
BACKGROUND AND OBJECTIVES.: To evaluate standard intravenous immunoglobulin IVIG as an alternative to intravenous cytomegalovirus hyperimmune immunoglobulin CMVIG for prophylaxis and therapy of cytomegalovirus CMV disease, we measured the ELISA and neutralizing titres of CMV-specific antibodies in CMVIG and IVIG preparations.
Cytomegalovirus neutralization by hyperimmune and standard intravenous immunoglobulin preparations. PubMed NCBI.
Although the expected high CMV IgG ELISA antibody titers were confirmed for three lots of a CMV hyperimmune preparation, the functionally more relevant CMV neutralizing antibody titers were significantly higher for 31 lots of standard IVIG preparations. Moreover, considerably lower IgG3 levels were found for the CMV hyperimmune preparation compared with standard IVIG preparations.

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