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hypericin
Definition of synthetic hypericin NCI Drug Dictionary National Cancer Institute.
John's' wort, with potential antineoplastic and photosensitizing activities. Upon topical administration of the ointment to the tumor site, hypericin becomes activated through the application of visible fluorescent light. During photoactivation, hypericin generates singlet oxygen, which induces DNA damage, necrosis and apoptosis, thereby inhibiting tumor cell growth.
A Phase I Dose Escalation Study of Synthetic Hypericin in HIV-Infected Patients With Less Than 300 CD4 Lymphocytes Full Text View ClinicalTrials.gov.
Hypericin is unlike other drugs presently being used to treat AIDS patients. Hypericin shows anti-HIV activity in test tube experiments. Each group of eight patients receives a given dose of hypericin by intravenous infusion. Doses are given three times per week for 8 weeks.
Hypericin C30H16O8, QUINONE Anthraquinone Extrasynthese.
Make a Search Products, Plants, Formula, MSDS, Specifications, Structures. Back to the list Hypericin. Code 0468 S. Sub family Anthraquinone. Formula C 30 H 16 O 8. Smiles CC1C2C3CCCCOC4C3C3C5C2CCOC1COC1C5CCOCC1OC1C3CCOCC1OC4O CC1C2C3CCCCOC4C3C3C5C2CCOC1COC1C5CCOCC1OC1C3CCOCC1OC4O. Hypericin analytical standard provided with w/w absolute assay, to be used for quantitative titration.
Hypericin Supplier CAS 548-04-9 Tocris Bioscience.
View all Broad Spectrum Protein Kinase Inhibitor Inhibitors. Keywords: Hypericin, Hypericin supplier, inhibitors, inhibits, tyrosine, kinases, Protein, Kinase, Broad, Spectrum, Inhibitors, Non-selective, Antivirals, 1520, Tocris Bioscience. 1 Citation for Hypericin. Citations are publications that use Tocris products. Selected citations for Hypericin include.:
Phenomenex Applications: Compound.
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St. Johns Wort Hypericin aidsinfonet.org The AIDS InfoNet.
Patients were given intravenous doses of purified hypericin. The study was stopped when every white-skinned patient in the trial became very sensitive to light. They developed skin rashes and some could not go outside until after they stopped taking hypericin.
Pre-Extraction and Extraction of Hypericin in St. John's' Wort Hypericum perforatum using the SpeedExtractor E-916 buchi.com.
Johns Wort herb and capsules with dry extract are widely used for the treatment of depressions. In this products hypericin is determined for quality reasons. The determination of the total amount of hypericin can be done by extraction and photometric quantification at 590 nm.
Hypericin A Napthodianthrone from Hypericum perforatum.
The hypericin content of Hypericum perforatum is determined by using spectroscopic method utilizing the visible absorption characteristics of hypericin in methyl alcohol. 19, 20 In atypical chromatogram of standardized Hypericum perforatum extract, absorbance occurs at 588nm and the peak.The peak at 10.67 min is characteristic of Hypericin.
Long-term effects of St. John's' wort and hypericin on monoamine levels in rat hypothalamus and hippocampus. PubMed NCBI.
John's' wort and hypericin, one of its major active compounds, on regional brain amine metabolism have not been reported yet. We used a high-performance liquid chromatography system to examine the effects of short-term 2 weeks and long-term 8 weeks administration of imipramine, Hypericum extract or hypericin on regional levels of serotonin 5-HT, norepinephrine, dopamine and their metabolites in the rat brain.
Fermentek Hypericin 548-04-9.
Soluble in alkaline aqueous solutions. Soluble in organic bases such as pyridine red fluorescent solutions but not in other organic solvents. Store in a freezer upon arrival, at 10C to 25C. Refer to MSDS for further safety and handling instructions.

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