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familial hypertrophic cardiomyopathy
Familial Hypertrophic Cardiomyopathy Mutations in the Regulatory Light Chains of Myosin Affect Their Structure, Ca2Binding, and Phosphorylation.
From the Department of Molecular and Cellular Pharmacology, University of Miami School of Medicine, Miami, Florida 33136 and the Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390. The effect of the familial hypertrophic cardiomyopathy mutations, A13T, F18L, E22K, R58Q, and P95A, found in the regulatory light chains of human cardiac myosin has been investigated.
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Malignant familial hypertrophic cardiomyopathy in a family with a 453ArgCys mutation in the myosin heavy chain gene: Coexistence of sudden death and end-stage heart failure SpringerLink.
Anan R, Greve G, Thierfelder L, Watkins HC, McKenna WJ, Solomon S, Vecchio C, Shono H, Nakao S, Tanaka H, Mares A Jr, Towbin JA, Spirito P, Roberts R, Seidman JG, Seidman CE 1994 Prognostic implications of novel cardiac myosin heavy chain gene mutations that cause familial hypertrophic cardiomyopathy.
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Familial hypertrophic cardiomyopathy Genetics Home Reference NIH.
CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 2. CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 3. CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 4. CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 6. CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 7. CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 8. CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 9. CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 10. CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 11. CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 12.
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Familial hypertrophic cardiomyopathy: malignant and variable phenotypes.
Familial hypertrophic cardiomyopathy: malignant and variable phenotypes. 05 Aug 2009. A whole family with inherited cardiomyopathy. The proband IV5: is a 38-year-old female who had the first diagnosis of hypertrophic cardiomyopathy at the age of 10 years. She has been asymptomatic for more than 20 years.
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Familial Hypertrophic Cardiomyopathy Circulation Research.
The results of molecular genetics studies have shown that familial hypertrophic cardiomyopathy is a disease of the sarcomere involving mutations in 7 different genes encoding proteins of the myofibrillar apparatus: myosin heavy chain, ventricular myosin essential light chain, ventricular myosin regulatory light chain, cardiac troponin T, cardiac troponin I, tropomyosin, and cardiac myosin binding protein C.
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Hypertrophic Hypertrophic Cardiomyopathy Cardiomyopathy American American Heart Heart Association. Association.
Ask your doctor what types and amounts of physical activity are safe for you. Other Names for Hypertrophic Cardiomyopathy. Asymmetric septal hypertrophy. Familial hypertrophic cardiomyopathy. Hypertrophic nonobstructive cardiomyopathy. Hypertrophic obstructive cardiomyopathy. Idiopathic hypertrophic subaortic stenosis IHSS. What causes hypertrophic cardiomyopathy?
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Hypertrophic cardiomyopathy Wikipedia.
Beta blockers are used in both cases, but treatment with diuretics, a mainstay of CHF treatment, will exacerbate symptoms in hypertrophic obstructive cardiomyopathy by decreasing ventricular preload volume and thereby increasing outflow resistance less blood to push aside the thickened obstructing tissue.
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Hypertrophic cardiomyopathy Symptoms and causes Mayo Clinic.
If you have a parent with hypertrophic cardiomyopathy, you have a 50% chance of having the genetic mutation for the disease. Parents, children or siblings of a person with hypertrophic cardiomyopathy should ask their doctors about screening for the disease.
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Genetics of Hypertrophic Cardiomyopathy After 20 Years: Clinical Perspectives ScienceDirect. ScienceDirect.
Under an Elsevier user license. Hypertrophic cardiomyopathy HCM is the most common familial heart disease with vast genetic heterogeneity, demonstrated over the past 20 years. Mutations in 11 or more genes encoding proteins of the cardiac sarcomere 1400, variants are responsible for or associated with HCM.
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Familial Hypertrophic Cardiomyopathy.
In high-risk individuals, an implantable cardioverter defibrillator may help prevent sudden cardiac arrest, a potential complication of hypertrophic cardiomyopathy. What is the Prognosis of Familial Hypertrophic Cardiomyopathy? The prognosis of Familial Hypertrophic Cardiomyopathy depends on early diagnosis, as well as prompt and sustained treatment.
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